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Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites
The avian IgY antibody isotype shares a common ancestor with both mammalian IgG and IgE and so provides a means to study the evolution of their structural and functional specialisations. Although both IgG and IgE bind to their leukocyte Fc receptors with 1:1 stoichiometry, IgY binds to CHIR-AB1, a r...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795851/ https://www.ncbi.nlm.nih.gov/pubmed/19733585 http://dx.doi.org/10.1016/j.dci.2009.08.012 |