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Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites

The avian IgY antibody isotype shares a common ancestor with both mammalian IgG and IgE and so provides a means to study the evolution of their structural and functional specialisations. Although both IgG and IgE bind to their leukocyte Fc receptors with 1:1 stoichiometry, IgY binds to CHIR-AB1, a r...

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Detalles Bibliográficos
Autores principales: Taylor, Alexander I., Sutton, Brian J., Calvert, Rosaleen A.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795851/
https://www.ncbi.nlm.nih.gov/pubmed/19733585
http://dx.doi.org/10.1016/j.dci.2009.08.012