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Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum

The extensive diversity of Plasmodium falciparum antigens is a major obstacle to a broadly effective malaria vaccine but population genetics has rarely been used to guide vaccine design. We have completed a meta-population genetic analysis of the genes encoding ten leading P. falciparum vaccine anti...

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Detalles Bibliográficos
Autores principales: Barry, Alyssa E., Schultz, Lee, Buckee, Caroline O., Reeder, John C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795866/
https://www.ncbi.nlm.nih.gov/pubmed/20041125
http://dx.doi.org/10.1371/journal.pone.0008497