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Detecting population stratification using related individuals

Although identification of cryptic population stratification is necessary for case/control association analyses, it is also vital for linkage analyses and family-based association tests when founder genotypes are missing. However, including related individuals in an analysis such as EIGENSTRAT can r...

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Detalles Bibliográficos
Autores principales: Hinrichs, Anthony L, Culverhouse, Robert, Jin, Carol H, Suarez, Brian K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795877/
https://www.ncbi.nlm.nih.gov/pubmed/20017970