Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method

Population structure occurs when a sample is composed of individuals with different ancestries and can result in excess type I error in genome-wide association studies. Genome-wide principal-component analysis (PCA) has become a popular method for identifying and adjusting for subtle population stru...

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Detalles Bibliográficos
Autores principales: Peloso, Gina M, Timofeev, Nadia, Lunetta, Kathryn L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795879/
https://www.ncbi.nlm.nih.gov/pubmed/20017972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795879/
https://www.ncbi.nlm.nih.gov/pubmed/20017972

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