Comparison of methods for correcting population stratification in a genome-wide association study of rheumatoid arthritis: principal-component analysis versus multidimensional scaling

Population stratification (PS) represents a major challenge in genome-wide association studies. Using the Genetic Analysis Workshop 16 Problem 1 data, which include samples of rheumatoid arthritis patients and healthy controls, we compared two methods that can be used to evaluate population structur...

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Detalles Bibliográficos
Autores principales: Wang, Dai, Sun, Yu, Stang, Paul, Berlin, Jesse A, Wilcox, Marsha A, Li, Qingqin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795880/
https://www.ncbi.nlm.nih.gov/pubmed/20017973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795880/
https://www.ncbi.nlm.nih.gov/pubmed/20017973

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