Cargando…

Accommodating population stratification in case-control association analysis: a new test and its application to genome-wide study on rheumatoid arthritis

It is well known that conventional association tests can lead to excessive false positives when there is population stratification. We propose a new test for detecting genetic association with a case-control study design. Unlike some other methods for handling population stratification, we treat the...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yufang, Xiao, Xiangjun, Wang, Kai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795883/
https://www.ncbi.nlm.nih.gov/pubmed/20017976