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Testing for genetic association taking into account phenotypic information of relatives

We investigated efficient case-control association analysis using family data. The outcome of interest was coronary heart disease. We employed existing and new methods that take into account the correlations among related individuals to obtain the proper type I error rates. The methods considered fo...

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Detalles Bibliográficos
Autores principales: Uh, Hae-Won, Wijk, Henk Jan van der, Houwing-Duistermaat, Jeanine J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795896/
https://www.ncbi.nlm.nih.gov/pubmed/20017989