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Effect of population stratification on the identification of significant single-nucleotide polymorphisms in genome-wide association studies

The North American Rheumatoid Arthritis Consortium case-control study collected case participants across the United States and control participants from New York. More than 500,000 single-nucleotide polymorphisms (SNPs) were genotyped in the sample of 2000 cases and controls. Careful adjustment for...

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Detalles Bibliográficos
Autores principales: Sarasua, Sara M, Collins, Julianne S, Williamson, Dhelia M, Satten, Glen A, Allen, Andrew S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795903/
https://www.ncbi.nlm.nih.gov/pubmed/20017996