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Analysis of genome-wide association data by large-scale Bayesian logistic regression

Single-locus analysis is often used to analyze genome-wide association (GWA) data, but such analysis is subject to severe multiple comparisons adjustment. Multivariate logistic regression is proposed to fit a multi-locus model for case-control data. However, when the sample size is much smaller than...

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Detalles Bibliográficos
Autores principales: Wang, Yuanjia, Sha, Nanshi, Fang, Yixin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795912/
https://www.ncbi.nlm.nih.gov/pubmed/20018005