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Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using penalized orthogonal-components regression

Genome-wide associations between single-nucleotide polymorphisms and clinical traits were simultaneously conducted using penalized orthogonal-components regression. This method was developed to identify the genetic variants controlling phenotypes from a massive number of candidate variants. By inves...

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Detalles Bibliográficos
Autores principales: Lin, Yanzhu, Zhang, Min, Wang, Libo, Pungpapong, Vitara, Fleet, James C, Zhang, Dabao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795917/
https://www.ncbi.nlm.nih.gov/pubmed/20018010