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Application of seventeen two-locus models in genome-wide association studies by two-stage strategy

The goal of this paper is to search for two-locus combinations that are jointly associated with rheumatoid arthritis using the data set of Genetic Analysis Workshop 16 Problem 1. We use a two-stage strategy to reduce the computational burden associated with performing an exhaustive two-locus search...

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Detalles Bibliográficos
Autores principales: Niu, Adan, Zhang, Zhaogong, Sha, Qiuying
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795923/
https://www.ncbi.nlm.nih.gov/pubmed/20018016