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Genome-wide association studies of rheumatoid arthritis data via multiple hypothesis testing methods for correlated tests

Genome-wide association studies often involve testing hundreds of thousands of single-nucleotide polymorphisms (SNPs). These tests may be highly correlated because of linkage disequilibrium among SNPs. Multiple testing correction ignoring the correlation among markers, as is done in the Bonferroni p...

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Detalles Bibliográficos
Autores principales: Kang, Guolian, Childers, Douglas K, Liu, Nianjun, Zhang, Kui, Gao, Guimin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795936/
https://www.ncbi.nlm.nih.gov/pubmed/20018029