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The effect of minor allele frequency on the likelihood of obtaining false positives
Determining the most promising single-nucleotide polymorphisms (SNPs) presents a challenge in genome-wide association studies, when hundreds of thousands of association tests are conducted. The power to detect genetic effects is dependent on minor allele frequency (MAF), and genome-wide association...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795940/ https://www.ncbi.nlm.nih.gov/pubmed/20018033 http://dx.doi.org/10.1186/1753-6561-3-S7-S41 |