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The effect of minor allele frequency on the likelihood of obtaining false positives

Determining the most promising single-nucleotide polymorphisms (SNPs) presents a challenge in genome-wide association studies, when hundreds of thousands of association tests are conducted. The power to detect genetic effects is dependent on minor allele frequency (MAF), and genome-wide association...

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Detalles Bibliográficos
Autores principales:	Tabangin, Meredith E, Woo, Jessica G, Martin, Lisa J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795940/ https://www.ncbi.nlm.nih.gov/pubmed/20018033 http://dx.doi.org/10.1186/1753-6561-3-S7-S41

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