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Assessment of genotype imputation methods

Several methods have been proposed to impute genotypes at untyped markers using observed genotypes and genetic data from a reference panel. We used the Genetic Analysis Workshop 16 rheumatoid arthritis case-control dataset to compare the performance of four of these imputation methods: IMPUTE, MACH,...

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Detalles Bibliográficos
Autores principales: Biernacka, Joanna M, Tang, Rui, Li, Jia, McDonnell, Shannon K, Rabe, Kari G, Sinnwell, Jason P, Rider, David N, de Andrade, Mariza, Goode, Ellen L, Fridley, Brooke L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795949/
https://www.ncbi.nlm.nih.gov/pubmed/20018042