Predictive modeling in case-control single-nucleotide polymorphism studies in the presence of population stratification: a case study using Genetic Analysis Workshop 16 Problem 1 dataset

In this paper, we apply the gradient-boosting machine predictive model to the rheumatoid arthritis data for predicting the case-control status. QQ-plot suggests severe population stratification. In univariate genome-wide association studies, a correction factor for ethnicity confounding can be deriv...

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Detalles Bibliográficos
Autores principales: Arshadi, Niloofar, Chang, Billy, Kustra, Rafal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795961/
https://www.ncbi.nlm.nih.gov/pubmed/20018054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795961/
https://www.ncbi.nlm.nih.gov/pubmed/20018054

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