Cargando…

Evaluation of single-nucleotide polymorphism imputation using random forests

Genome-wide association studies (GWAS) have helped to reveal genetic mechanisms of complex diseases. Although commonly used genotyping technology enables us to determine up to a million single-nucleotide polymorphisms (SNPs), causative variants are typically not genotyped directly. A favored approac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schwarz, Daniel F, Szymczak, Silke, Ziegler, Andreas, König, Inke R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795966/ https://www.ncbi.nlm.nih.gov/pubmed/20018059

Ejemplares similares

Picking single-nucleotide polymorphisms in forests
por: Schwarz, Daniel F, et al.
Publicado: (2007)

ACPA: automated cluster plot analysis of genotype data
por: Schillert, Arne, et al.
Publicado: (2009)

Detecting significant single-nucleotide polymorphisms in a rheumatoid arthritis study using random forests
por: Wang, Minghui, et al.
Publicado: (2009)

Joint analysis of sequence data and single-nucleotide polymorphism data using pedigree information for imputation and recombination inference
por: Song, Sunah, et al.
Publicado: (2014)

Classification of rheumatoid arthritis status with candidate gene and genome-wide single-nucleotide polymorphisms using random forests
por: Sun, Yan V, et al.
Publicado: (2007)

Two-stage approach for identifying single-nucleotide polymorphisms associated with rheumatoid arthritis using random forests and Bayesian networks
por: Meng, Yan, et al.
Publicado: (2007)

Genetic association studies for gene expressions: permutation-based mutual information in a comparison with standard ANOVA and as a novel approach for feature selection
por: Szymczak, Silke, et al.
Publicado: (2007)

Haplotype-sharing analysis for alcohol dependence based on quantitative traits and the Mantel statistic
por: Kleensang, Andre, et al.
Publicado: (2005)

Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method
por: Xie, Qian, et al.
Publicado: (2005)

Look who is calling: a comparison of genotype calling algorithms
por: Vens, Maren, et al.
Publicado: (2009)

Comparison of collapsing methods for the statistical analysis of rare variants
por: Dering, Carmen, et al.
Publicado: (2011)

A comparison of two collapsing methods in different approaches
por: Dering, Carmen, et al.
Publicado: (2014)

Selection of single-nucleotide polymorphisms in disease association data
por: Joo, Jungnam, et al.
Publicado: (2005)

Single versus multiple imputation for genotypic data
por: Fridley, Brooke L, et al.
Publicado: (2009)

Comparison of tagging single-nucleotide polymorphism methods in association analyses
por: Goode, Ellen L, et al.
Publicado: (2007)

Modeling the effect of an associated single-nucleotide polymorphism in linkage studies
por: Houwing-Duistermaat, Jeanine J, et al.
Publicado: (2005)

Comparison of single-nucleotide polymorphisms and microsatellites in inference of population structure
por: Liu, Nianjun, et al.
Publicado: (2005)

The efficacy of short tandem repeat polymorphisms versus single-nucleotide polymorphisms for resolving population structure
por: Kauwe, John SK, et al.
Publicado: (2005)

The impact of single nucleotide polymorphism selection on prediction of genomewide breeding values
por: Żukowski, Kacper, et al.
Publicado: (2009)

An analysis of identical single-nucleotide polymorphisms genotyped by two different platforms
por: Suarez, Brian K, et al.
Publicado: (2005)

Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium
por: Duggal, Priya, et al.
Publicado: (2005)

Strategies for selecting subsets of single-nucleotide polymorphisms to genotype in association studies
por: Butler, Joe M, et al.
Publicado: (2005)

A comparison of five methods for selecting tagging single-nucleotide polymorphisms
por: Burkett, Kelly M, et al.
Publicado: (2005)

Linkage and association analyses of microsatellites and single-nucleotide polymorphisms in nuclear families
por: Lin, Jennifer, et al.
Publicado: (2005)

Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms
por: Cho, Kelly, et al.
Publicado: (2007)

Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures
por: Dunn, Gerald, et al.
Publicado: (2005)

Linkage disequilibrium across two different single-nucleotide polymorphism genome scans
por: Peralta, Juan Manuel, et al.
Publicado: (2005)

A comparison between microsatellite and single-nucleotide polymorphism markers with respect to two measures of information content
por: Thalamuthu, Anbupalam, et al.
Publicado: (2005)

Application of sex-specific single-nucleotide polymorphism filters in genome-wide association data
por: Ling, Hua, et al.
Publicado: (2009)

Empirically derived subgroups in rheumatoid arthritis: association with single-nucleotide polymorphisms on chromosome 6
por: Wilcox, Marsha A, et al.
Publicado: (2007)

Linkage analysis of complex diseases using microsatellites and single-nucleotide polymorphisms: application to alcoholism
por: Nsengimana, Jérémie, et al.
Publicado: (2005)

Comparing single-nucleotide polymorphism marker-based and microsatellite marker-based linkage analyses
por: Ulgen, Ayse, et al.
Publicado: (2005)

Assessment of genotype imputation methods
por: Biernacka, Joanna M, et al.
Publicado: (2009)

Linkage analysis of alcoholism-related electrophysiological phenotypes: genome scans with microsatellites compared to single-nucleotide polymorphisms
por: Bautista, Jocelyn F, et al.
Publicado: (2005)

Linkage analysis of the GAW14 simulated dataset with microsatellite and single-nucleotide polymorphism markers in large pedigrees
por: Yang, Xiaohong (Rose), et al.
Publicado: (2005)

Detecting single-nucleotide polymorphism by single-nucleotide polymorphism interactions in rheumatoid arthritis using a two-step approach with machine learning and a Bayesian threshold least absolute shrinkage and selection operator (LASSO) model
por: González-Recio, Oscar, et al.
Publicado: (2009)

Effect of population stratification on the identification of significant single-nucleotide polymorphisms in genome-wide association studies
por: Sarasua, Sara M, et al.
Publicado: (2009)

Simultaneous analysis of all single-nucleotide polymorphisms in genome-wide association study of rheumatoid arthritis
por: Mathew, George, et al.
Publicado: (2009)

Identifying single-nucleotide polymorphisms responsible for the linkage signal of rheumatoid arthritis on chromosome 6 by joint modeling of linkage and association
por: Lin, Wan-Yu, et al.
Publicado: (2007)

Comparison of genome-wide single-nucleotide polymorphism linkage analyses in Caucasian and Hispanic NARAC families
por: Chen, Wei V, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_6cf2dj9iseivalq924jls75a91