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Single versus multiple imputation for genotypic data

Due to the growing need to combine data across multiple studies and to impute untyped markers based on a reference sample, several analytical tools for imputation and analysis of missing genotypes have been developed. Current imputation methods rely on single imputation, which ignores the variation...

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Detalles Bibliográficos
Autores principales: Fridley, Brooke L, McDonnell, Shannon K, Rabe, Kari G, Tang, Rui, Biernacka, Joanna M, Sinnwell, Jason P, Rider, David N, Goode, Ellen L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795971/
https://www.ncbi.nlm.nih.gov/pubmed/20018064