Different models and single-nucleotide polymorphisms signal the simulated weak gene-gene interaction for a quantitative trait using haplotype-based and mixed models testing

Knowledge of simulated genetic effects facilitates interpretation of methodological studies. Genetic interactions for common disorders are likely numerous and weak. Using the 200 replicates of the Genetic Analysis Workshop 16 (GAW16) Problem 3 simulated data, we compared the statistical power to det...

Descripción completa

Detalles Bibliográficos
Autores principales: Kovac, Ilija P, Dubé, Marie-Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795979/
https://www.ncbi.nlm.nih.gov/pubmed/20018072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795979/
https://www.ncbi.nlm.nih.gov/pubmed/20018072

Ejemplares similares