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Assessment of gene-covariate interactions by incorporating covariates into association mapping

The HLA region is considered to be the main genetic risk factor for rheumatoid arthritis. Previous research demonstrated that HLA-DRB1 alleles encoding the shared epitope are specific for disease that is characterized by antibodies to cyclic citrullinated peptides (anti-CCP). In the present study, w...

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Detalles Bibliográficos
Autores principales: Chiu, Yen-Feng, Kao, Hui-Yi, Chen, Yi-Shin, Hsu, Fang-Chi, Yang, Hsin-Chou
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795988/
https://www.ncbi.nlm.nih.gov/pubmed/20018081