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Assessment of gene-covariate interactions by incorporating covariates into association mapping
The HLA region is considered to be the main genetic risk factor for rheumatoid arthritis. Previous research demonstrated that HLA-DRB1 alleles encoding the shared epitope are specific for disease that is characterized by antibodies to cyclic citrullinated peptides (anti-CCP). In the present study, w...
Autores principales: | Chiu, Yen-Feng, Kao, Hui-Yi, Chen, Yi-Shin, Hsu, Fang-Chi, Yang, Hsin-Chou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795988/ https://www.ncbi.nlm.nih.gov/pubmed/20018081 |
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