Diverse Hematological Malignancies Including Hodgkin-Like Lymphomas Develop in Chimeric MHC Class II Transgenic Mice

A chimeric HLA-DR4-H2-E (DR4) homozygous transgenic mouse line spontaneously develops diverse hematological malignancies with high frequency (70%). The majority of malignancies were distributed equally between T and B cell neoplasms and included lymphoblastic T cell lymphoma (LTCL), lymphoblastic B...

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Detalles Bibliográficos
Autores principales: Raffegerst, Silke H., Hoelzlwimmer, Gabriele, Kunder, Sandra, Mysliwietz, Josef, Quintanilla-Martinez, Leticia, Schendel, Dolores J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796171/
https://www.ncbi.nlm.nih.gov/pubmed/20046882
http://dx.doi.org/10.1371/journal.pone.0008539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796171/
https://www.ncbi.nlm.nih.gov/pubmed/20046882
http://dx.doi.org/10.1371/journal.pone.0008539

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