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Diverse Hematological Malignancies Including Hodgkin-Like Lymphomas Develop in Chimeric MHC Class II Transgenic Mice

A chimeric HLA-DR4-H2-E (DR4) homozygous transgenic mouse line spontaneously develops diverse hematological malignancies with high frequency (70%). The majority of malignancies were distributed equally between T and B cell neoplasms and included lymphoblastic T cell lymphoma (LTCL), lymphoblastic B...

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Detalles Bibliográficos
Autores principales:	Raffegerst, Silke H., Hoelzlwimmer, Gabriele, Kunder, Sandra, Mysliwietz, Josef, Quintanilla-Martinez, Leticia, Schendel, Dolores J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796171/ https://www.ncbi.nlm.nih.gov/pubmed/20046882 http://dx.doi.org/10.1371/journal.pone.0008539

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