Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics

Proteomic and lipidomic profiling was performed over a time course of acute hepatitis C virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular processes influenced by this virus. Our proteomic data suggest that HCV induces early perturbations in glycolysis, the p...

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Detalles Bibliográficos
Autores principales: Diamond, Deborah L., Syder, Andrew J., Jacobs, Jon M., Sorensen, Christina M., Walters, Kathie-Anne, Proll, Sean C., McDermott, Jason E., Gritsenko, Marina A., Zhang, Qibin, Zhao, Rui, Metz, Thomas O., Camp, David G., Waters, Katrina M., Smith, Richard D., Rice, Charles M., Katze, Michael G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796172/
https://www.ncbi.nlm.nih.gov/pubmed/20062526
http://dx.doi.org/10.1371/journal.ppat.1000719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796172/
https://www.ncbi.nlm.nih.gov/pubmed/20062526
http://dx.doi.org/10.1371/journal.ppat.1000719

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