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Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics
Proteomic and lipidomic profiling was performed over a time course of acute hepatitis C virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular processes influenced by this virus. Our proteomic data suggest that HCV induces early perturbations in glycolysis, the p...
Autores principales: | Diamond, Deborah L., Syder, Andrew J., Jacobs, Jon M., Sorensen, Christina M., Walters, Kathie-Anne, Proll, Sean C., McDermott, Jason E., Gritsenko, Marina A., Zhang, Qibin, Zhao, Rui, Metz, Thomas O., Camp, David G., Waters, Katrina M., Smith, Richard D., Rice, Charles M., Katze, Michael G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796172/ https://www.ncbi.nlm.nih.gov/pubmed/20062526 http://dx.doi.org/10.1371/journal.ppat.1000719 |
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