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Bone Marrow Transplantation Results in Human Donor Blood Cells Acquiring and Displaying Mouse Recipient Class I MHC and CD45 Antigens on Their Surface

BACKGROUND: Mouse models of human disease are invaluable for determining the differentiation ability and functional capacity of stem cells. The best example is bone marrow transplants for studies of hematopoietic stem cells. For organ studies, the interpretation of the data can be difficult as trans...

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Detalles Bibliográficos
Autores principales: Yamanaka, Nobuko, Wong, Christine J., Gertsenstein, Marina, Casper, Robert F., Nagy, Andras, Rogers, Ian M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796175/
https://www.ncbi.nlm.nih.gov/pubmed/20046883
http://dx.doi.org/10.1371/journal.pone.0008489