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Bone Marrow Transplantation Results in Human Donor Blood Cells Acquiring and Displaying Mouse Recipient Class I MHC and CD45 Antigens on Their Surface
BACKGROUND: Mouse models of human disease are invaluable for determining the differentiation ability and functional capacity of stem cells. The best example is bone marrow transplants for studies of hematopoietic stem cells. For organ studies, the interpretation of the data can be difficult as trans...
Autores principales: | Yamanaka, Nobuko, Wong, Christine J., Gertsenstein, Marina, Casper, Robert F., Nagy, Andras, Rogers, Ian M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796175/ https://www.ncbi.nlm.nih.gov/pubmed/20046883 http://dx.doi.org/10.1371/journal.pone.0008489 |
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