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Abnormal Placental Development and Early Embryonic Lethality in EpCAM-Null Mice

BACKGROUND: EpCAM (CD326) is encoded by the tacstd1 gene and expressed by a variety of normal and malignant epithelial cells and some leukocytes. Results of previous in vitro experiments suggested that EpCAM is an intercellular adhesion molecule. EpCAM has been extensively studied as a potential tum...

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Detalles Bibliográficos
Autores principales: Nagao, Keisuke, Zhu, Jianjian, Heneghan, Mallorie B., Hanson, Jeffrey C., Morasso, Maria I., Tessarollo, Lino, Mackem, Susan, Udey, Mark C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796178/
https://www.ncbi.nlm.nih.gov/pubmed/20046825
http://dx.doi.org/10.1371/journal.pone.0008543