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Identification of a Mechanical Rheostat in the Hydrophobic Core of Protein L

The ability of proteins and their complexes to withstand or respond to mechanical stimuli is vital for cells to maintain their structural organisation, to relay external signals and to facilitate unfolding and remodelling. Force spectroscopy using the atomic force microscope allows the behaviour of...

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Detalles Bibliográficos
Autores principales: Sadler, David P., Petrik, Eva, Taniguchi, Yukinori, Pullen, James R., Kawakami, Masaru, Radford, Sheena E., Brockwell, David J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796179/
https://www.ncbi.nlm.nih.gov/pubmed/19683005
http://dx.doi.org/10.1016/j.jmb.2009.08.015