Conformational Transitions upon Ligand Binding: Holo-Structure Prediction from Apo Conformations

Biological function of proteins is frequently associated with the formation of complexes with small-molecule ligands. Experimental structure determination of such complexes at atomic resolution, however, can be time-consuming and costly. Computational methods for structure prediction of protein/liga...

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Detalles Bibliográficos
Autores principales: Seeliger, Daniel, de Groot, Bert L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796265/
https://www.ncbi.nlm.nih.gov/pubmed/20066034
http://dx.doi.org/10.1371/journal.pcbi.1000634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796265/
https://www.ncbi.nlm.nih.gov/pubmed/20066034
http://dx.doi.org/10.1371/journal.pcbi.1000634

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