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Combining Structure and Sequence Information Allows Automated Prediction of Substrate Specificities within Enzyme Families
An important aspect of the functional annotation of enzymes is not only the type of reaction catalysed by an enzyme, but also the substrate specificity, which can vary widely within the same family. In many cases, prediction of family membership and even substrate specificity is possible from enzyme...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796266/ https://www.ncbi.nlm.nih.gov/pubmed/20072606 http://dx.doi.org/10.1371/journal.pcbi.1000636 |