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Cyclooxygenase-2 Expression Is Related to the Epithelial-to-Mesenchymal Transition in Human Colon Cancers

PURPOSE: Down-regulation of E-cadherin is a hallmark of the epithelial-to-mesenchymal transition (EMT). EMT progression in cancer cells is associated with the loss of certain epithelial markers and the acquisition of a mesenchymal phenotype, as well as migratory activities. Cyclooxygenase-2 (COX-2)...

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Detalles Bibliográficos
Autores principales: Jang, Tae Jung, Jeon, Kyu Ha, Jung, Ki Hoon
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796410/
https://www.ncbi.nlm.nih.gov/pubmed/20046424
http://dx.doi.org/10.3349/ymj.2009.50.6.818