Targeting the Epidermal Growth Factor Receptor in Epithelial Ovarian Cancer: Current Knowledge and Future Challenges

The epidermal growth factor receptor is overexpressed in up to 60% of ovarian epithelial malignancies. EGFR regulates complex cellular events due to the large number of ligands, dimerization partners, and diverse signaling pathways engaged. In ovarian cancer, EGFR activation is associated with incre...

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Detalles Bibliográficos
Autores principales: Siwak, Doris R., Carey, Mark, Hennessy, Bryan T., Nguyen, Catherine T., McGahren Murray, Mollianne J., Nolden, Laura, Mills, Gordon B.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796463/
https://www.ncbi.nlm.nih.gov/pubmed/20037743
http://dx.doi.org/10.1155/2010/568938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796463/
https://www.ncbi.nlm.nih.gov/pubmed/20037743
http://dx.doi.org/10.1155/2010/568938

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