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Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R αA-crystallin
Purpose: Crystallins are major functional and structural proteins in mammalian lens. Their expression, distribution, and protein–protein interaction affect lens development and fiber cell differentiation. Mutated crystallins lead to structural and functional changes of lens structure and could lead...
Autores principales: | Gong, Bo, Zhang, Li-Yun, Pang, Chi-Pui, Lam, Dennis Shun-Chiu, Yam, Gary Hin-Fai |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796635/ https://www.ncbi.nlm.nih.gov/pubmed/20029648 |
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