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Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers

BACKGROUND: The aim of this study was to compare the pharmacokinetic properties of sodium ibuprofen and ibuprofen acid incorporating poloxamer with standard ibuprofen acid tablets. METHODS: Twenty-two healthy volunteers were enrolled into this randomised, single-dose, 3-way crossover, open-label, si...

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Detalles Bibliográficos
Autores principales: Dewland, Peter M, Reader, Sandie, Berry, Phillip
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796637/
https://www.ncbi.nlm.nih.gov/pubmed/19961574
http://dx.doi.org/10.1186/1472-6904-9-19