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Profound human/mouse differences in alpha-dystrobrevin isoforms: a novel syntrophin-binding site and promoter missing in mouse and rat

BACKGROUND: The dystrophin glycoprotein complex is disrupted in Duchenne muscular dystrophy and many other neuromuscular diseases. The principal heterodimeric partner of dystrophin at the heart of the dystrophin glycoprotein complex in the main clinically affected tissues (skeletal muscle, heart and...

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Detalles Bibliográficos
Autores principales: Böhm, Sabrina V, Constantinou, Panayiotis, Tan, Sipin, Jin, Hong, Roberts, Roland G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796648/
https://www.ncbi.nlm.nih.gov/pubmed/19961569
http://dx.doi.org/10.1186/1741-7007-7-85