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Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania

BACKGROUND: Leishmania parasites must overcome several barriers to achieve transmission by their sand fly vectors. One of the earliest threats is exposure to enzymes during blood meal digestion. Trypsin-like enzymes appear to be detrimental to parasite survival during the very early phase of develop...

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Detalles Bibliográficos
Autores principales: Sant'Anna, Mauricio RV, Diaz-Albiter, Hector, Mubaraki, Murad, Dillon, Rod J, Bates, Paul A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796656/
https://www.ncbi.nlm.nih.gov/pubmed/20003192
http://dx.doi.org/10.1186/1756-3305-2-62