Identification of colorectal cancer patients with tumors carrying the TP53 mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy

BACKGROUND: Although postoperative chemotherapy is widely accepted as the standard modality for Dukes' stage C or earlier stage colorectal cancer (CRC) patients, biomarkers to predict those who may benefit from the therapy have not been identified. Previous in vitro and clinical investigations...

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Detalles Bibliográficos
Autores principales: Godai, Ten-i, Suda, Tetsuji, Sugano, Nobuhiro, Tsuchida, Kazuhito, Shiozawa, Manabu, Sekiguchi, Hironobu, Sekiyama, Akiko, Yoshihara, Mitsuyo, Matsukuma, Shoichi, Sakuma, Yuji, Tsuchiya, Eiju, Kameda, Yoichi, Akaike, Makoto, Miyagi, Yohei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796677/
https://www.ncbi.nlm.nih.gov/pubmed/19954513
http://dx.doi.org/10.1186/1471-2407-9-420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796677/
https://www.ncbi.nlm.nih.gov/pubmed/19954513
http://dx.doi.org/10.1186/1471-2407-9-420

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