Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile

The human REL proto-oncogene encodes a transcription factor in the NF-κB family. Overexpression of REL is acutely transforming in chicken lymphoid cells, but has not been shown to transform any mammalian lymphoid cell type. In this report, we show that overexpression of a highly transforming mutant...

Descripción completa

Detalles Bibliográficos
Autores principales: Chin, M, Herscovitch, M, Zhang, N, Waxman, DJ, Gilmore, TD
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796798/
https://www.ncbi.nlm.nih.gov/pubmed/19377508
http://dx.doi.org/10.1038/onc.2009.74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796798/
https://www.ncbi.nlm.nih.gov/pubmed/19377508
http://dx.doi.org/10.1038/onc.2009.74

Ejemplares similares