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2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association

In placental mammals, inactivation of one of the X chromosomes in female cells ensures sex chromosome dosage compensation. The 17 kb non-coding Xist RNA is crucial to this process and accumulates on the future inactive X chromosome. The most conserved Xist RNA region, the A region, contains eight or...

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Detalles Bibliográficos
Autores principales: Maenner, Sylvain, Blaud, Magali, Fouillen, Laetitia, Savoye, Anne, Marchand, Virginie, Dubois, Agnès, Sanglier-Cianférani, Sarah, Van Dorsselaer, Alain, Clerc, Philippe, Avner, Philip, Visvikis, Athanase, Branlant, Christiane
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796953/
https://www.ncbi.nlm.nih.gov/pubmed/20052282
http://dx.doi.org/10.1371/journal.pbio.1000276