Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistance

BACKGROUND: Occludin is a tetraspanin protein normally localized to tight junctions. The protein interacts with a variety of pathogens including viruses and bacteria, an interaction that sometimes leads to its extrajunctional localization. RESULTS: Here we report that treatment of mammary epithelial...

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Detalles Bibliográficos
Autores principales: Beeman, Neal E, Baumgartner, Heidi K, Webb, Patricia G, Schaack, Jerome B, Neville, Margaret C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796999/
https://www.ncbi.nlm.nih.gov/pubmed/20003227
http://dx.doi.org/10.1186/1471-2121-10-85

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796999/
https://www.ncbi.nlm.nih.gov/pubmed/20003227
http://dx.doi.org/10.1186/1471-2121-10-85

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