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An experimental assessment of in silico haplotype association mapping in laboratory mice

BACKGROUND: To assess the utility of haplotype association mapping (HAM) as a quantitative trait locus (QTL) discovery tool, we conducted HAM analyses for red blood cell count (RBC) and high density lipoprotein cholesterol (HDL) in mice. We then experimentally tested each HAM QTL using published cro...

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Detalles Bibliográficos
Autores principales: Burgess-Herbert, Sarah L, Tsaih, Shirng-Wern, Stylianou, Ioannis M, Walsh, Kenneth, Cox, Allison J, Paigen, Beverly
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797012/
https://www.ncbi.nlm.nih.gov/pubmed/20003225
http://dx.doi.org/10.1186/1471-2156-10-81