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A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial drugs

BACKGROUND: In order to provide a cost-effective tool to analyse pharmacogenetic markers in malaria treatment, DNA microarray technology was compared with sequencing of polymerase chain reaction (PCR) fragments to detect single nucleotide polymorphisms (SNPs) in a larger number of samples. METHODS:...

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Detalles Bibliográficos
Autores principales: Hodel, Eva Maria, Ley, Serej D, Qi, Weihong, Ariey, Frédéric, Genton, Blaise, Beck, Hans-Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797017/
https://www.ncbi.nlm.nih.gov/pubmed/20003204
http://dx.doi.org/10.1186/1475-2875-8-285