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Understanding the HIV coreceptor switch from a dynamical perspective

BACKGROUND: The entry of HIV into its target cells is facilitated by the prior binding to the cell surface molecule CD4 and a secondary coreceptor, mostly the chemokine receptors CCR5 or CXCR4. In early infection CCR5-using viruses (R5 viruses) are mostly dominant while a receptor switch towards CXC...

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Detalles Bibliográficos
Autor principal: Kamp, Christel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797020/
https://www.ncbi.nlm.nih.gov/pubmed/19948048
http://dx.doi.org/10.1186/1471-2148-9-274