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Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes

BACKGROUND: Tumor-specific cytotoxic T cells and infiltrating lymphocytes are frequently found in tumor tissues in patients with nasopharyngeal carcinoma (NPC). Most patients with NPC, however, especially those with advanced stages, have a poor clinical prognosis despite conventional immunotherapy....

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Detalles Bibliográficos
Autores principales: Liu, Peng, Xie, Bai-Lu, Cai, Shao-Hui, He, Yun-Wen, Zhang, Ge, Yi, Yan-Mei, Du, Jun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797021/
https://www.ncbi.nlm.nih.gov/pubmed/19948041
http://dx.doi.org/10.1186/1471-2407-9-416