Dopamine receptor loss of function is not protective of rd1 rod photoreceptors in vivo

PURPOSE: The retinal degeneration (rd1) mouse undergoes a rapid loss of rod photoreceptors due to a defect in the cGMP-phosphodiesterase gene. We have previously demonstrated that dopamine (DA) antagonists or DA depletion blocks photoreceptor degeneration and that DA is necessary for photoreceptor d...

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Detalles Bibliográficos
Autores principales: Ogilvie, Judith Mosinger, Hakenewerth, Angela M., Gardner, Rachel R., Martak, Joshua G., Maggio, Virginia M.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797042/
https://www.ncbi.nlm.nih.gov/pubmed/20038975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797042/
https://www.ncbi.nlm.nih.gov/pubmed/20038975

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