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An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer

Emerging evidence indicates that gene products implicated in human cancers often cluster together in “hot spots” in protein-protein interaction (PPI) networks. Additionally, small sub-networks within PPI networks that demonstrate synergistic differential expression with respect to tumorigenic phenot...

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Detalles Bibliográficos
Autores principales: Nibbe, Rod K., Koyutürk, Mehmet, Chance, Mark R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797084/
https://www.ncbi.nlm.nih.gov/pubmed/20090827
http://dx.doi.org/10.1371/journal.pcbi.1000639