Cargando…

Plasma Levels of Transforming Growth Factor-β1 Reflect Left Ventricular Remodeling in Aortic Stenosis

BACKGROUND: TGF-β1 is involved in cardiac remodeling through an auto/paracrine mechanism. The contribution of TGF-β1 from plasmatic source to pressure overload myocardial remodeling has not been analyzed. We investigated, in patients with valvular aortic stenosis (AS), and in mice subjected to trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Villar, Ana V., Cobo, Manuel, Llano, Miguel, Montalvo, Cecilia, González-Vílchez, Francisco, Martín-Durán, Rafael, Hurlé, María A., Nistal, J. Francisco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797091/
https://www.ncbi.nlm.nih.gov/pubmed/20041033
http://dx.doi.org/10.1371/journal.pone.0008476