Automated Discovery of Novel Drug Formulations Using Predictive Iterated High Throughput Experimentation

BACKGROUND: We consider the problem of optimizing a liposomal drug formulation: a complex chemical system with many components (e.g., elements of a lipid library) that interact nonlinearly and synergistically in ways that cannot be predicted from first principles. METHODOLOGY/PRINCIPAL FINDINGS: The...

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Detalles Bibliográficos
Autores principales: Caschera, Filippo, Gazzola, Gianluca, Bedau, Mark A., Bosch Moreno, Carolina, Buchanan, Andrew, Cawse, James, Packard, Norman, Hanczyc, Martin M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797296/
https://www.ncbi.nlm.nih.gov/pubmed/20049327
http://dx.doi.org/10.1371/journal.pone.0008546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797296/
https://www.ncbi.nlm.nih.gov/pubmed/20049327
http://dx.doi.org/10.1371/journal.pone.0008546

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