Cargando…
Automated Discovery of Novel Drug Formulations Using Predictive Iterated High Throughput Experimentation
BACKGROUND: We consider the problem of optimizing a liposomal drug formulation: a complex chemical system with many components (e.g., elements of a lipid library) that interact nonlinearly and synergistically in ways that cannot be predicted from first principles. METHODOLOGY/PRINCIPAL FINDINGS: The...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797296/ https://www.ncbi.nlm.nih.gov/pubmed/20049327 http://dx.doi.org/10.1371/journal.pone.0008546 |